Flow-Cyt,Fixed in 4 % formaldehyde and permeabilized with 90 % methanol. 1 μL per 1 x 10^6 cells.,ICC,140 to 1100. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE cell sections.,IHC,140 to 1100. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.,WB,11000
Restrictions
For Research Use only
Format
Liquid
Concentration
400 μg/mL
Buffer
Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
2 - 8 °C
Expiry Date
12 months
Target
JDP2
(Jun Dimerization Protein 2 (JDP2))
Alternative Name
JDP2
Background
JDP2 is a component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. JDP2 is involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. It can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8WYK2].